Research Interests:

My research focuses on combining transcriptomics, molecular indicators, in vitro cell assays, along with traditional toxicological and environmental measurements, to determine the effect of legacy compounds and chemicals of emerging concern (CEC) effect fish development and reproductive health. My research has two main themes: 1) the use of laboratory and field studies to identify known and novel adverse outcome pathways from exposure to low-level legacy compounds and CECs; and 2) measuring the fate and transport of chemicals in the aquatic environment through the use of in vitro and in vivo bioassays;

Selected Publications:

Crago, J., Xu, E., Kupsco, A., Jia, F., Mehinto, A., Maruya, K., Gan, J., Schlenk, D. in review. In vitro bioassessment of trophic transfer and comparisons with field monitoring of residues and effects of DDTs in sediments and male hornyhead turbot (Pleuronichthys verticalis) of Palos Verdes, CA (USA). Environmental Pollution 213, 940-948.

Crago, J., Bui, C., Grewal, S., Schlenk, D. accepted. Age-dependent effects in fathead minnows from the anti-diabetic drug metformin. General and Comparative Endocrinology 232, 185-190.

Mehinto, A., Jia, A., Snyder, S. Jayasinghe, S., Denslow, N., Crago, J., Schlenk, D. Menzie, C., Westerheide, S., Leusch, F., Maruya, K. 2015. Interlaboratory comparison of in vitro bioassays for screening of endocrine disrupting chemicals in recycled water. Water Research 83, 303-9.

Crago, J., Schlenk, D., 2015. The effect of bifenthrin on the dopaminergic-GnRH pathway in juvenile rainbow trout. Aquatic Toxicol. 162, 66-72.

Crago, J, Tran, K., Budicin, A., Schreiber, B., Lavado, R., Schlenk, D., 2014. Exploring the cause of estrogenic activity in male fathead minnows from a mixture of pesticide and surfactants. Arch Environ Contam Toxicol. 68, 362-70.

Jia, F., Bao, L-J., Crago, J., Schlenk, D., Gan, J., 2014. Use of isotope dilution method to predict bioavailability of organic pollutants in historically contaminated sediments. Environ Sci Technol. 48, 7966-7973.

Escher, B., Allinson, M., Altenburger, R., Bain, P., Balaguer, Patrick; Busch, Wibke; Crago, J., et al.  Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays. Env. Sci Technol. 48, 1940-1956.